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Jefferson Avenue and East Grand Boulevard. Shown below circa 1936.

My guess on the make of automobile is A Buick Model 10 (produced from 1908 - 1911). This appears to be a runabout version without the back seat. Very sporty, no matter what.
The driver of that car sure looks a lot like Fred G. Sanford to me...the G is for gasoline.
The home on the left is a great house. Even when wages were only a dollar a day, there have been people that could do things that would make them rich. I think that is wonderful.
The illegible shopfront sign got me curious, so I rummaged around in the LOC's Detroit Publishing Co. images that included automobiles. There are two more views of this street scene in the collection, taken at slightly different times, but each with a passing car. The LOC cataloger devised the titles from scrutiny of the original 5x7 glass negatives, listing one as "Street with automobile and Moesta's store," (LC-D418-31165) and the other as "Street with Moesta's store and Fuller Savings Bank" (LC-D418-31166). I'm not sure that the reading of "Store" is quite right, since the S-word looks longer than that in the image posted here, but the "Moesta" seems correct. There don't seem to be any other online references to these businesses, but a Moesta family genealogy page (a German surname later anglicized to Mesta) suggests Pittsburgh, PA as a possible locale for the period of the photo.
Danged hot-rodders!
Seriously, can anyone make out the model of the car?
This looks to have been in an upper-class neighborhood. Look at the size of the houses and how clean everything was. Also, no packs of "feral children" are running wild in the streets!
What are the words in the window of the building to the far right?
[Too blurry to tell. - Dave]
Put me down as one owner; got them about 35 years ago, kept the leather (hand) part nearly soaked in mink oil. The long fur sleeves are wonderful, used them today with the temps in the teens. Snowmobile used to call them "snot-wipers," the furry part being perfectly located for that work.
I think this is Elinor Blevins in disguise. How many paople would own a pair of gloves like that?
I've got a horseless carriage and you guys DON'T!
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