1942 or 1943. "Gilead, Ohio (?), possibly Mount Gilead" is the uncertain caption. Although the photo does provide a few clues. 35mm Kodachrome transparency by John Vachon for the Farm Security Administration.
UPDATE: A couple of astute commenters have identified this as a building on Main Street in Mount Orab, Ohio. Google Street View gives a pretty good match
. If there are any Shorpyite shutterbugs in Mount Orab, hie on over to the intersection of Main and High, send us some pics and help us lay to rest a mystery that's been bedeviling the Library of Congress for the past 65 years! | Click image for Comments.