This looks to be Grand Street just north of Broadway (there is no Grant St. in Newburgh). Newburgh was one of several cities on the periphery of New York City where plays would be performed to work out the kinks before moving to Broadway and many of the big name performers would stay at the Palatine.

The hotel, like much of downtown Newburgh, was demolished in 1970 in one of the most shameful and racist urban renewal programs in US history. The building to the right with the arched windows was the YMCA and is now the Newburgh Adult Learning Center.

I have been a fan of Shorpy for many years and I am still fascinated by the pristine buildings, concrete sidewalks and beautiful decor of the time, but dirt roads right in the middle of the cities!