"The North American", seen on the building in the distance, was a newspaper published in Philadelphia from 1839 to 1925, sometimes under slightly different names.

Nailing down exactly what its slogans were is proving a little more difficult. Here, it's
"-ERALD OF - POLITICS -R MORALS". A picture from 1909 reveals that the slogan had changed to "A Sane Exponent of -", but the rest is blocked by another sign.

Below is the same view from October of 2013. This appears to have been taken just a few minutes after this view https://www.shorpy.com/node/20036.

"Wilson Whiskey
That's all."

-- is a startlingly modern ad compared to the wordy and ornate ads more typical of the period. It could easily fit on the back page of any magazine published from the 1970s to the present.

I wonder if it worked, or if the guy who created it got fired for having ideas that were just too weird?

houses the The Right Worshipful Grand Lodge of the Most Ancient and Honorable Fraternity of Free and Accepted Masons of Pennsylvania and Masonic Jurisdictions Thereunto Belonging and

was designed in the medieval Norman style by James H. Windrim, who was 27 years old at the time he won the design competition. The massive granite cornerstone, weighing ten tons, was leveled on St. John the Baptist's Day, June 24, 1868. The ceremonial gavel used on that day by Grand Master Richard Vaux was the same gavel used by President George Washington in leveling the cornerstone of the nation's Capitol building in 1793.
....
On May 27, 1971, the Temple was listed on the National Register of Historic Places. It was designated a National Historic Landmark in 1985. It was cited in its landmark designation as one of the nation's most elaborate examples of Masonic architecture.

It may be a little blurry, but I believe the sole automobile on the left is a brand new Curved Dash Oldsmobile.